BDBM50012187 INDIRUBIN 2
SMILES O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(Br)cc12
InChI Key InChIKey=TYNCGTPANDPODX-WAVHTBQISA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50012187
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant 5-LO assessed as product formation by cell-free assay relative to controlMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 20 uM A23187/AA ionopho...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 2.5 uM A23187 ionophoreMore data for this Ligand-Target Pair